KXD1 and STX11

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KXD1	STX11
Description		KxDL motif containing 1	syntaxin 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane BLOC-1 Complex BORC Complex	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Vesicle-mediated Transport Lysosome Localization	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion
Pathways
Drugs
Diseases			Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS			Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		42 interacting genes: APPL1 ARHGDIG C4orf46 CCDC185 CCDC33 CEP170P1 CEP19 CEP63 COLGALT1 DYRK2 ELOA2 EWSR1 EXOC5 EXOC7 FXR2 GABARAPL1 HAUS1 IFT20 ING5 ITSN2 KRT81 LMO3 LNX1 LRRC45 MAP1LC3A MAP1LC3B MCRS1 MOB1A MYH7 NIF3L1 NUDT18 RABGEF1 RNF183 RPL9 STX11 TCEA2 TPM1 TPM3 UTP6 ZBTB25 ZC4H2 ZNF417	64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587
Entrez ID		79036	8676
HPRD ID		14526	09231
Ensembl ID		ENSG00000105700	ENSG00000135604
Uniprot IDs		A0A024R7M2 Q9BQD3	O75558
PDB IDs
Enriched GO Terms of Interacting Partners?
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