DDR1 and NCK2

  • Number of citations of the paper that reports this interaction (PubMedID 16337946)
  • 15
  • Data Source:
  • HPRD (two hybrid)

DDR1

NCK2

Description discoidin domain receptor tyrosine kinase 1 NCK adaptor protein 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related macular degeneration ( 23455636)
  • Arterial stiffness index ( 31235810)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • HIV-1 control ( 20041166)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Microalbuminuria in type 1 diabetes ( 31537649)
  • Response to hepatitis B vaccine ( 29534301)
  • Rosacea symptom severity ( 29771307)
  • Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848)
  • Schizophrenia ( 30285260)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Takayasu arteritis ( 25604533)
  • Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
  • Ulcerative colitis ( 20848476)
  • Addiction ( 23533358)
  • Platelet distribution width ( 27863252)
  • Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes 19 interacting genes: BEND5 BRD2 COL11A1 COL2A1 COL3A1 COL5A2 ERBB2 FRS2 MAPK6 NCK2 NUDT3 PLCG1 PTPN11 RGS2 SHC1 SNAPIN SNRNP40 TM4SF1 TTR 87 interacting genes: ABI1 ABI2 ABI3 ARHGAP32 ATN1 AXIN1 AXL BCL11A CBLB CCDC33 CD3E CHN1 CPSF6 CPSF7 DDR1 DNM1 DOCK1 DOK1 DRAP1 DVL1 EEF1G EFHC2 EFNB1 EFNB2 EFS EGFR EIF3H ERBB2 ERBB3 FAM53C FASLG FCRL2 FGFR1 FXR2 FYB1 HNRNPK HOMEZ HOXC4 ILK IRS1 KHDRBS1 KIAA1217 LCP2 LIMS1 LNX1 LRRIQ3 LZTS2 MAGEA6 MASP1 MEOX2 NCKIPSD NPHS1 NR5A1 NTRK2 PAK1 PDGFRB PIK3AP1 PKD1 PKN2 PRR20A PSMD10 PTK2 RASSF7 RBM26 REL SF3B4 SKAP2 SMARCB1 SORBS2 SOS1 SPRY2 SRPK1 SRPK2 SYNPO TCF4 TNR TRIM27 TRIM41 TRIP6 UBC VARS2 VPS37B WAS WASL WBP11 WIPF2 ZBTB7B
Entrez ID 780 8440
HPRD ID 02678 05378
Ensembl ID ENSG00000204580 ENSG00000071051
Uniprot IDs A0A024RCJ0 A0A024RCL1 A0A024RCQ1 A0A0A0MSX3 Q08345 Q96T61 Q96T62 A0A0S2Z4M6 E7ERP6 O43639
PDB IDs 3ZOS 4AG4 4BKJ 4CKR 5BVK 5BVN 5BVO 5BVW 5FDP 5FDX 6BRJ 6BSD 6FEW 6FEX 6FIL 6FIN 6FIO 6FIQ 6GWR 6HP9 1U5S 1WX6 1Z3K 2B86 2CIA 2FRW 2FRY 2JXB 4E6R
Enriched GO Terms of Interacting Partners?
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