TRIM26 and OTUB2

Number of citations of the paper that reports this interaction (PubMedID 23105109)
16

Data Source:
BioGRID (two hybrid)

		TRIM26	OTUB2
Description		tripartite motif containing 26	OTU deubiquitinase, ubiquitin aldehyde binding 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus Cytosol	Nucleus
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding NEDD8-specific Protease Activity Ubiquitin Binding
	Biological Process	Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Viral Release From Host Cell	Protein Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways		Interferon gamma signaling	Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401) Neuroticism ( 29255261) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 21926974 22883433 30285260) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		20 interacting genes: INCA1 IRF3 LMNA MAGEA6 MNAT1 OTUB2 PHF7 RABEP1 RNF10 RNF126 SUMO2 THAP1 TLE5 TRIM41 UBE2D1 UBE2D2 UBE2D3 USP36 USP39 USP5	35 interacting genes: APP ARRDC3 CPSF6 FAM168A GLI2 KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 PJA1 RBCK1 REL RFFL RNF126 SIAH1 TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 U2AF2 UBC UBE2N USP21 USP28
Entrez ID		7726	78990
HPRD ID		02901	07620
Ensembl ID		ENSG00000234127	ENSG00000089723
Uniprot IDs		A0A024RCP3 Q12899	Q96DC9
PDB IDs			1TFF 4FJV
Enriched GO Terms of Interacting Partners?
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