SF1 and RBM7

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		SF1	RBM7
Description		splicing factor 1	RNA binding motif protein 7
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome Nuclear Body	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding	RNA Binding Single-stranded RNA Binding Protein Binding SnRNA Binding 14-3-3 Protein Binding Pre-mRNA Intronic Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Male Sex Determination Nuclear Body Organization Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	Regulation Of Alternative MRNA Splicing, Via Spliceosome SnRNA Catabolic Process Meiotic Cell Cycle
Pathways		mRNA Splicing - Major Pathway
Drugs		Artenimol
Diseases
GWAS		Urate levels ( 21768215)	Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		43 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	14 interacting genes: CCDC85B CHERP DHX8 HMG20A HNRNPK HYOU1 KHDRBS1 KHDRBS3 RBM4 RBMX SF1 SF3B2 SRSF3 ZCCHC8
Entrez ID		7536	10179
HPRD ID		03306	11488
Ensembl ID		ENSG00000168066	ENSG00000076053
Uniprot IDs		A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637	G3V1T9 J3KPD3 Q9Y580
PDB IDs		1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX	2M8H 5IQQ 5LXR 5LXY
Enriched GO Terms of Interacting Partners?
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