WRN and RPA1

  • Number of citations of the paper that reports this interaction (PubMedID 10373438)
  • 113
  • Data Source:
  • HPRD (in vivo, in vitro)

WRN

RPA1

Description WRN RecQ like helicase replication protein A1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronotype ( 30696823)
  • Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903)
  • Daytime sleep phenotypes ( 27126917)
  • Exercise treadmill test traits ( 17903301)
  • Fasting glucose change (long-term) ( 31263163)
  • Intelligence (MTAG) ( 29326435)
  • Lifespan ( 25918517)
  • Logical memory (delayed recall) in mild cognitive impairment ( 29274321)
  • Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
  • Metabolite levels ( 23823483)
  • Morning person ( 30696823)
Interacting Genes 34 interacting genes: ATM ATRX BARD1 BLM BRCA1 CDKN2A FEN1 H2AX MDC1 MDM2 PARP1 PCNA POLB POLD2 POLK POLR1C PRKAR1B PRKDC RAD1 RAD51 RAD52 RAD54B RAD9A RPA1 SUMO1 SUMO2 TERF2 TP53 UBE2D2 UBXN8 VCP WRNIP1 XRCC5 XRCC6 65 interacting genes: AICDA AKTIP ANXA1 ANXA7 ASCC2 ATM BID BLM BRCA2 BRIP1 CCNA1 CCNA2 CCNB1 CDC5L CPE CSNK2B DMC1 EHMT2 ERCC1 ERCC4 EXO5 GNB5 HAX1 HELB HGH1 HNRNPUL1 HUS1 MCM2 MCM4 MCM6 MCM7 MMS22L MSH4 MTUS2 MUTYH ORC2 ORC6 PAXIP1 PCNA POLL PRKDC RAD1 RAD23B RAD51 RAD52 RAD9A RBM23 RCC1 RECQL RFWD3 RPA2 RPA3 RPA4 RPS6KA5 SELENBP1 SEM1 SMAD3 TCEA2 TK1 TP53 TREX1 VIM WRN XPA XPC
Entrez ID 7486 6117
HPRD ID 05212 01565
Ensembl ID ENSG00000165392 ENSG00000132383
Uniprot IDs Q14191 P27694
PDB IDs 2AXL 2DGZ 2E1E 2E1F 2FBT 2FBV 2FBX 2FBY 2FC0 3AAF 1EWI 1FGU 1JMC 1L1O 2B29 2B3G 4IJH 4IJL 4IPC 4IPD 4IPG 4IPH 4LUO 4LUV 4LUZ 4LW1 4LWC 4NB3 4O0A 4R4C 4R4I 4R4O 4R4Q 4R4T 5E7N 5EAY 5N85 5N8A
Enriched GO Terms of Interacting Partners?
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