VDAC1 and TOMM20

Number of citations of the paper that reports this interaction (PubMedID 9119086)
8

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		VDAC1	TOMM20
Description		voltage dependent anion channel 1	translocase of outer mitochondrial membrane 20
Image
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Synaptic Vesicle Membrane Mitochondrial Nucleoid Membrane Raft Pore Complex Extracellular Exosome	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Integral Component Of Mitochondrial Outer Membrane Mitochondria-associated ER Membrane
	Molecular Function	Protein Binding Voltage-gated Anion Channel Activity Porin Activity Protein Kinase Binding Identical Protein Binding Ion Channel Binding Protein-containing Complex Binding	Protein Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding Unfolded Protein Binding
	Biological Process	Behavioral Fear Response Pyruvate Metabolic Process Anion Transport Mitochondrial Calcium Ion Transmembrane Transport Apoptotic Process Neuron-neuron Synaptic Transmission Learning Inorganic Anion Transport Viral Process Macroautophagy Epithelial Cell Differentiation Anion Transmembrane Transport Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Reactive Oxygen Species Metabolic Process	Protein Targeting To Mitochondrion Response To Muscle Activity TRNA Import Into Mitochondrion Macroautophagy Protein Deubiquitination Protein Import Into Mitochondrial Matrix Mitochondrial Outer Membrane Translocase Complex Assembly Response To 3,3',5-triiodo-L-thyronine
Pathways		Mitochondrial protein import Pink/Parkin Mediated Mitophagy Ub-specific processing proteases Pyruvate metabolism Mitochondrial calcium ion transport	Mitochondrial protein import Pink/Parkin Mediated Mitophagy Ub-specific processing proteases
Drugs		Aluminium monostearate
Diseases
GWAS		Alopecia areata ( 25608926) Metabolite levels ( 23823483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Cholesterol, total ( 20686565) Cobalt levels ( 26025379) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)
Interacting Genes		22 interacting genes: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PPIF PRKCE PRKN RAF1 RNF31 SUMO4 TOMM20 TUBA4A	19 interacting genes: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 CEP126 DHFR FBXO7 FEZ1 HAP1 HSD17B10 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1
Entrez ID		7416	9804
HPRD ID		05137	03507
Ensembl ID		ENSG00000213585	ENSG00000173726
Uniprot IDs		A0A1L1UHR1 B3KTS5 P21796	A0A024R3W2 Q15388
PDB IDs		2JK4 2K4T 5JDP 5XDN 5XDO 6G6U 6G73	4APO
Enriched GO Terms of Interacting Partners?
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