USF1 and USF2

Number of citations of the paper that reports this interaction (PubMedID 8576131)
56

Data Source:
HPRD (in vitro, in vivo)

		USF1	USF2
Description		upstream transcription factor 1	upstream transcription factor 2, c-fos interacting
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex	Nuclear Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Double-stranded DNA Binding Protein Binding Enzyme Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Protein Heterodimerization Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Hypoxia Glucose Metabolic Process Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Response To UV Late Viral Transcription Cellular Response To Insulin Stimulus Glucose Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Carbon Catabolite Regulation Of Transcription Negative Regulation Of Fibrinolysis Lipid Homeostasis	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Transcription By RNA Polymerase II Lactation Late Viral Transcription Positive Regulation Of Transcription By RNA Polymerase II Lipid Homeostasis
Pathways		Estrogen-dependent gene expression	Estrogen-dependent gene expression
Drugs
Diseases		Familial combined hyperlipidemia (FCHL)
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 23128233) Metabolite levels (lipoprotein measures) ( 27005778) Night sleep phenotypes ( 27126917)	Adverse response to drug ( 30420678) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		16 interacting genes: APP ESR1 FBXO7 FOS FOSL1 GTF2I HDAC9 NFYA PLEKHF2 PPARGC1A PRKDC TAOK2 TCF3 TCFL5 TRAF2 USF2	10 interacting genes: BRCA1 EP300 FOS LZTS2 MAF NFYA PPARGC1A RELA TEAD2 USF1
Entrez ID		7391	7392
HPRD ID		01880	02668
Ensembl ID		ENSG00000158773	ENSG00000105698
Uniprot IDs		A0A0S2Z4U5 P22415	Q15853
PDB IDs		1AN4
Enriched GO Terms of Interacting Partners?
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