UQCRC1 and UQCRC2

Number of citations of the paper that reports this interaction (PubMedID 11073949)
16

Data Source:
HPRD (in vitro)

		UQCRC1	UQCRC2
Description		ubiquinol-cytochrome c reductase core protein 1	ubiquinol-cytochrome c reductase core protein 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Mitochondrial Respiratory Chain Complex III Cytosol	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex IV Mitochondrial Processing Peptidase Complex
	Molecular Function	Ubiquinol-cytochrome-c Reductase Activity Ubiquitin Protein Ligase Binding Protein-containing Complex Binding Metal Ion Binding	Endopeptidase Activity Metalloendopeptidase Activity Protein Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration Response To Activity Response To Alkaloid Oxidation-reduction Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Protein Processing Involved In Protein Targeting To Mitochondrion Aerobic Respiration Response To Drug
Pathways		Respiratory electron transport	Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Myxothiazol 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE FAMOXADONE METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE UBIQUINONE-2	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE FAMOXADONE METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE UBIQUINONE-2
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Metabolite levels ( 23823483) Ulcerative colitis ( 28067908)
Interacting Genes		8 interacting genes: CYCS GPX1 HNRNPD KRAS NLGN3 RTN4 TRIM63 UQCRC2	3 interacting genes: CACNA1A RTN4 UQCRC1
Entrez ID		7384	7385
HPRD ID		01875	01876
Ensembl ID		ENSG00000010256	ENSG00000140740
Uniprot IDs		P31930	P22695
PDB IDs		5XTE 5XTH 5XTI	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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