UBE2G2 and CNNM3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		UBE2G2	CNNM3
Description		ubiquitin conjugating enzyme E2 G2	cyclin and CBS domain divalent metal cation transport mediator 3
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GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Transmembrane Transporter Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Transport Ion Transport Transmembrane Transport
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Birth weight ( 31043758) Erectile dysfunction and prostate cancer treatment ( 20932654) Offspring birth weight ( 31043758)
Interacting Genes		38 interacting genes: AMFR ARL14 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4	19 interacting genes: CBY2 CCNDBP1 FHL3 HNRNPK KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP3-2 KRTAP4-12 KRTAP5-9 LZTS2 MDFI PNMA1 PTP4A2 RBPMS RELA UBE2G2 USHBP1
Entrez ID		7327	26505
HPRD ID		04387	07419
Ensembl ID		ENSG00000184787	ENSG00000168763
Uniprot IDs		P60604	Q8NE01
PDB IDs		2CYX 2KLY 2LXP 3H8K 4LAD	5K22 5K23 5K25 5TSR 6DFD 6MN6
Enriched GO Terms of Interacting Partners?
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