TUBG1 and OLA1

Number of citations of the paper that reports this interaction (PubMedID 24289923)
19

Data Source:
BioGRID (pull down)

		TUBG1	OLA1
Description		tubulin gamma 1	Obg like ATPase 1
Image
GO Annotations	Cellular Component	Pericentriolar Material Condensed Nuclear Chromosome Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Centriole Spindle Polar Microtubule Cytosol Microtubule Cytoplasmic Microtubule Cell Leading Edge Ciliary Basal Body Apical Part Of Cell Recycling Endosome Non-motile Cilium	Extracellular Region Nucleolus Cytoplasm Centrosome Cytosol Membrane Platelet Alpha Granule Lumen Extracellular Exosome
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Identical Protein Binding	Protein Binding ATP Binding GTP Binding ATPase Activity Ribosome Binding Ribosomal Large Subunit Binding Cadherin Binding Metal Ion Binding
	Biological Process	Mitotic Sister Chromatid Segregation G2/M Transition Of Mitotic Cell Cycle Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Microtubule Nucleation Mitotic Spindle Organization Regulation Of G2/M Transition Of Mitotic Cell Cycle Cytoplasmic Microtubule Organization Ciliary Basal Body-plasma Membrane Docking	Platelet Degranulation ATP Metabolic Process
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Platelet degranulation
Drugs		Vinblastine
Diseases
GWAS			Blood protein levels ( 30072576) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Hand grip strength ( 29691431) Reaction time ( 29844566) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 30224653)
Interacting Genes		29 interacting genes: APP BRCA1 CENPJ CNTN2 CUL4A DDX41 IKBKG KIF14 KRT18 KRT19 MARK4 NAPG NDE1 OLA1 PCNT PIK3R1 PLK1 PXN RACGAP1 RACK1 RASSF1 RNF19A RPGR SPATC1 TUBA1B TUBA3C TUBB4B TUBGCP3 TUBGCP4	7 interacting genes: ASCC2 BARD1 BRCA1 HMGA1 PRMT5 RACK1 TUBG1
Entrez ID		7283	29789
HPRD ID		01853	15194
Ensembl ID		ENSG00000131462	ENSG00000138430
Uniprot IDs		P23258	Q9NTK5
PDB IDs		1Z5V 1Z5W 3CB2	2OHF
Enriched GO Terms of Interacting Partners?
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