TRH and TRHR

Number of citations of the paper that reports this interaction (PubMedID 15117874)
3

Data Source:
HPRD (in vitro, in vivo)

		TRH	TRHR
Description		thyrotropin releasing hormone	thyrotropin releasing hormone receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Plasma Membrane Secretory Granule	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Thyrotropin-releasing Hormone Activity	Thyrotropin-releasing Hormone Receptor Activity
	Biological Process	Histamine Metabolic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Hormone-mediated Signaling Pathway Negative Regulation Of Glutamate Secretion Positive Regulation Of Gamma-aminobutyric Acid Secretion Positive Regulation Of Insulin Secretion Eating Behavior	G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			Protirelin
Diseases
GWAS		Alzheimer's disease ( 30636644) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Body mass (lean) ( 19268274) Daytime sleep phenotypes ( 27126917) Night sleep phenotypes ( 27126917) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969)
Interacting Genes		3 interacting genes: ARRB2 CPE TRHR	2 interacting genes: ARRB1 TRH
Entrez ID		7200	7201
HPRD ID		08944	11767
Ensembl ID		ENSG00000170893	ENSG00000174417
Uniprot IDs		P20396	P34981
PDB IDs
Enriched GO Terms of Interacting Partners?
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