TPM3 and OIP5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		TPM3	OIP5
Description		tropomyosin 3	Opa interacting protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromocenter Cajal Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Protein Binding Actin Filament Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Muscle Contraction Actin Filament Organization Muscle Filament Sliding	Cell Cycle Chromosome Segregation Cell Communication CENP-A Containing Nucleosome Assembly Cell Division
Pathways		Striated Muscle Contraction Smooth Muscle Contraction	Deposition of new CENPA-containing nucleosomes at the centromere
Drugs		Phenethyl Isothiocyanate
Diseases		Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS		Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Ulcerative colitis ( 28067908)
Interacting Genes		44 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 DVL2 FAM9C FBXO5 HDDC3 HOOK2 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 NOD2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P	22 interacting genes: ABL2 BRAF C1orf94 CASP10 CEP170P1 EIF4ENIF1 FOXJ1 GCC1 HJURP KDM1A KRT15 NUP62 PEX19 RAF1 RARG SKIL TFIP11 TMPO TPM3 TRIP6 TSSK3 VPS39
Entrez ID		7170	11339
HPRD ID		01840	09352
Ensembl ID		ENSG00000143549	ENSG00000104147
Uniprot IDs		A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753	A0A024R9N0 O43482
PDB IDs		6OTN
Enriched GO Terms of Interacting Partners?
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