TNNC1 and TNNI1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vivo)

		TNNC1	TNNI1
Description		troponin C1, slow skeletal and cardiac type	troponin I1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex Cardiac Troponin Complex	Cytosol Troponin Complex
	Molecular Function	Calcium Ion Binding Protein Binding Troponin I Binding Troponin T Binding Protein Homodimerization Activity Calcium-dependent Protein Binding Actin Filament Binding	Actin Binding Protein Binding Metal Ion Binding
	Biological Process	Diaphragm Contraction Skeletal Muscle Contraction Regulation Of Muscle Contraction Response To Metal Ion Transition Between Fast And Slow Fiber Muscle Filament Sliding Regulation Of Muscle Filament Sliding Speed Regulation Of ATPase Activity Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction	Skeletal Muscle Contraction Muscle Contraction Regulation Of Striated Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs		Trifluoperazine Levosimendan Felodipine Bepridil Calcium Aluminium monostearate 5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Feeling worry ( 29500382) Schizophrenia ( 23974872)
Interacting Genes		12 interacting genes: CDK1 MST1 POLR2G RBM15B TCP10L TNNI1 TNNI2 TNNI3 TNNT1 TNNT2 TRIM63 UBE2C	10 interacting genes: ACTA1 CCDC85B MDFI PKD2L1 PNMA1 TNNC1 TNNT1 TNNT2 TRIM55 TRIM63
Entrez ID		7134	7135
HPRD ID		08930	01842
Ensembl ID		ENSG00000114854	ENSG00000159173
Uniprot IDs		P63316 Q6FH91	P19237
PDB IDs		1AP4 1IH0 1J1D 1J1E 1LXF 1MXL 1OZS 1SPY 1WRK 1WRL 2JT0 2JT3 2JT8 2JTZ 2JXL 2KDH 2KFX 2KGB 2KRD 2L1R 2L98 2MKP 2MLE 2MLF 2MZP 2N79 2N7L 3RV5 3SD6 3SWB 4GJE 4GJF 4GJG 4Y99 5VLN 5W88 5WCL 6MV3
Enriched GO Terms of Interacting Partners?
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