SEC62 and CIC

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SEC62	CIC
Description		SEC62 homolog, preprotein translocation factor	capicua transcriptional repressor
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Signaling Receptor Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding
	Biological Process	Cotranslational Protein Targeting To Membrane Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Posttranslational Protein Targeting To Membrane, Translocation	Negative Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development
Pathways
Drugs
Diseases
GWAS		Cadmium levels ( 26025379)	Bitter alcoholic beverage consumption ( 31046077)
Interacting Genes		4 interacting genes: CIC GLUD1 SEC63 ZNF24	14 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GTPBP3 NFYC PICK1 PLD3 PLK1 PYCR2 SEC62 SETD2 TRIM22 ZNRD1
Entrez ID		7095	23152
HPRD ID		03706	10831
Ensembl ID		ENSG00000008952	ENSG00000079432
Uniprot IDs		D3DNQ1 Q99442	A0A0A0MQR4 Q96RK0
PDB IDs			2M41 4J2J 4J2L 6JRP
Enriched GO Terms of Interacting Partners?
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