TG and ASGR1

Number of citations of the paper that reports this interaction (PubMedID 12477859)
27

Data Source:
HPRD (in vivo)

		TG	ASGR1
Description		thyroglobulin	asialoglycoprotein receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Hormone Activity Identical Protein Binding	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Metal Ion Binding
	Biological Process	Thyroid Hormone Generation Signal Transduction Iodide Transport Thyroid Gland Development Regulation Of Myelination Hormone Biosynthetic Process	Receptor-mediated Endocytosis Viral Process Protein N-linked Glycosylation Via Asparagine Cellular Response To Extracellular Stimulus
Pathways			Asparagine N-linked glycosylation
Drugs
Diseases		Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Bone erosion in rheumatoid arthritis ( 28512992) Graves' disease ( 23612905) Hyperthyroidism ( 30367059) Hypothyroidism ( 27182965) Medication use (thyroid preparations) ( 31015401) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Temperament ( 22832960) Thyroid stimulating hormone levels ( 30367059) Vitiligo ( 27723757)	Liver enzyme levels (alkaline phosphatase) ( 22001757) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 31666285 29403010)
Interacting Genes		9 interacting genes: APCS ASGR1 CANX CTSD CTSL HSP90B1 HSPA5 LRP2 P4HB	14 interacting genes: APP ASGR2 CERS2 CLEC4G DHFR HIVEP1 HSP90AA1 HSP90B1 LAMTOR5 LMNA NLK RBBP6 TG VKORC1
Entrez ID		7038	432
HPRD ID		01782	00151
Ensembl ID		ENSG00000042832	ENSG00000141505
Uniprot IDs		P01266	P07306 Q6FGQ5
PDB IDs			1DV8 5JPV 5JQ1
Enriched GO Terms of Interacting Partners?
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