TEAD1 and VGLL2

Number of citations of the paper that reports this interaction (PubMedID 12376544)
47

Data Source:
HPRD (in vitro, in vivo)

		TEAD1	VGLL2
Description		TEA domain transcription factor 1	vestigial like family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex TEAD-1-YAP Complex	Nucleus Cytoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Coactivator Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Protein C-terminus Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Protein-containing Complex Assembly Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II	Skeletal Muscle Tissue Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Central retinal vein equivalent ( 26567291) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diisocyanate-induced asthma ( 25918132) HDL cholesterol levels x loop diuretics use interaction ( 31806883) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435)	Creatine kinase levels ( 29403010) Diastolic blood pressure ( 27841878) Facial emotion recognition (fearful faces) ( 28608620) Height ( 20881960 31562340) Lung cancer ( 28604730) Night sleep phenotypes ( 27126917) Serum total protein level ( 29403010) Waist-hip ratio ( 28552196)
Interacting Genes		17 interacting genes: BORCS8-MEF2B GCAT HLA-DMB INSR MAX MEF2A MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17	3 interacting genes: MEF2C TEAD1 TEAD3
Entrez ID		7003	245806
HPRD ID		01802	18282
Ensembl ID		ENSG00000187079	ENSG00000170162
Uniprot IDs		P28347 Q59EF3	Q8N8G2
PDB IDs		2HZD 3KYS 4RE1 4Z8E 5NNX 6HIL 6IM5
Enriched GO Terms of Interacting Partners?
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