TBX6 and HSFY1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		TBX6	HSFY1
Description		T-box transcription factor 6	heat shock transcription factor Y-linked 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Mesoderm Formation Cell Fate Specification Heart Looping Mesoderm Development Anatomical Structure Morphogenesis Negative Regulation Of Neuron Projection Development Negative Regulation Of Neuron Maturation Signal Transduction Involved In Regulation Of Gene Expression Somite Rostral/caudal Axis Specification Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II	Cellular Response To Heat Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Heat Stress
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Eosinophil counts ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244) Red blood cell count ( 29403010 27863252) Schizophrenia ( 25056061 29483656) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		7 interacting genes: C1orf94 HSFY1 MEOX2 PRMT1 PSMA3 RBPMS TOX4	13 interacting genes: BANP GCM2 HGS HNRNPF JAK2 QRICH1 RBFOX1 RBM47 RBPMS SMARCB1 SOX15 SV2B TBX6
Entrez ID		6911	86614
HPRD ID		03888	11850
Ensembl ID		ENSG00000149922	ENSG00000172468
Uniprot IDs		O95947	Q96LI6
PDB IDs
Enriched GO Terms of Interacting Partners?
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