TAF7 and TAF8

Number of citations of the paper that reports this interaction (PubMedID 14580349)
21

Data Source:
HPRD (in vitro, in vivo)

		TAF7	TAF8
Description		TATA-box binding protein associated factor 7	TATA-box binding protein associated factor 8
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GO Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex Transcription Factor TFIID Complex Golgi Apparatus Transcription Factor TFTC Complex MLL1 Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Perinuclear Region Of Cytoplasm
	Molecular Function	TFIIH-class Transcription Factor Complex Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Histone Acetyltransferase Binding Vitamin D Receptor Binding Transcription Regulatory Region DNA Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity H3K27me3 Modified Histone Binding P-TEFb Complex Binding	Protein Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spermine Transport DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Histone Acetylation Negative Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Histone H4 Acetylation Regulation Of Signal Transduction By P53 Class Mediator	Inner Cell Mass Cell Proliferation Cell Differentiation SnRNA Transcription By RNA Polymerase II Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Maintenance Of Protein Location In Nucleus
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252)	Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		27 interacting genes: AHR CDK7 CDK9 CPSF1 FAU GATA1 H3-4 HSF1 IKBKG MAP1LC3B RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1	13 interacting genes: H3-4 KPNA2 KPNB1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9
Entrez ID		6879	129685
HPRD ID		07196	18167
Ensembl ID		ENSG00000178913	ENSG00000137413
Uniprot IDs		Q15545	Q7Z7C8
PDB IDs		4RGW 5FUR 6MZL 6MZM	4WV4 4WV6 5FUR 6MZC 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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