STAT4 and ZNF467

Number of citations of the paper that reports this interaction (PubMedID 12426389)
8

Data Source:
HPRD (in vitro)

		STAT4	ZNF467
Description		signal transducer and activator of transcription 4	zinc finger protein 467
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytosol	Nucleus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	DNA Binding Metal Ion Binding
	Biological Process	Defense Response JAK-STAT Cascade Cytokine-mediated Signaling Pathway Interleukin-12-mediated Signaling Pathway Interleukin-21-mediated Signaling Pathway Interleukin-23-mediated Signaling Pathway Regulation Of Cell Proliferation Response To Peptide Hormone Positive Regulation Of Transcription By RNA Polymerase II Interleukin-35-mediated Signaling Pathway	Regulation Of Transcription, DNA-templated
Pathways		Interleukin-20 family signaling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation Interleukin-35 Signalling Interleukin-12 signaling Interleukin-12 signaling Interleukin-23 signaling Interleukin-21 signaling	Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Behcet's disease ( 23001997 23291587) Celiac disease ( 22057235 25920553) Celiac disease and Rheumatoid arthritis ( 26546613) Celiac disease or Rheumatoid arthritis ( 21383967) Gamma glutamyl transferase levels ( 29403010) Generalized epilepsy ( 30531953) Hepatocellular carcinoma in hepatitis B infection ( 23242368) Idiopathic inflammatory myopathy ( 26362759) Inflammatory bowel disease ( 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Limited cutaneous systemic scleroderma ( 29293537) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244 24076602) Nontyphoidal Salmonella bacteraemia ( 29523850) Primary biliary cholangitis ( 28425483 23000144 21399635 26394269) Primary biliary cirrhosis ( 22961000) Rheumatoid arthritis ( 30423114 23143596 24390342 20453841 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) SjÃ¶gren's syndrome ( 24097066 24097067 28076899) Systemic lupus erythematosus ( 27399966 24871463 26606652 23273568 26663301 23053960 26316170 26502338 18204098 21408207 19165918 28714469 19838193 19838195) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 28314753 24387989 21750679 31672989 20383147 29293537 21779181) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Vitiligo ( 27723757)	Metabolite levels ( 31628463) Pulse pressure ( 30224653)
Interacting Genes		14 interacting genes: ADRB2 CREBBP CRK IL12RB1 IL12RB2 JUN MAP2K6 MAPK14 NMI PIAS2 SH2D1B STAT1 STAT3 ZNF467	3 interacting genes: STAT1 STAT3 STAT4
Entrez ID		6775	168544
HPRD ID		02779	18343
Ensembl ID		ENSG00000138378	ENSG00000181444
Uniprot IDs		Q14765	C9JAX3 Q7Z7K2
PDB IDs
Enriched GO Terms of Interacting Partners?
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