TRIM21 and MAP1LC3C

Number of citations of the paper that reports this interaction (PubMedID 26347139)
65

Data Source:
BioGRID (pull down)

		TRIM21	MAP1LC3C
Description		tripartite motif containing 21	microtubule associated protein 1 light chain 3 gamma
Image
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Autophagosome Cytosol SCF Ubiquitin Ligase Complex Cytoplasmic Vesicle Ribonucleoprotein Complex	Autophagosome Membrane Autophagosome Cytosol Microtubule Endomembrane System Organelle Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	DNA Binding RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Polyubiquitination Protein Monoubiquitination Cell Cycle Positive Regulation Of Autophagy Protein Ubiquitination Protein Destabilization Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Type I Interferon Production Negative Regulation Of Viral Transcription Response To Interferon-gamma Innate Immune Response Positive Regulation Of Cell Cycle Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Protein Autoubiquitination Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Protein Deubiquitination Negative Regulation Of Viral Release From Host Cell	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Protein Exit From Endoplasmic Reticulum Aggrephagy Autophagosome Maturation
Pathways		STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA Interferon gamma signaling Antigen processing: Ubiquitination & Proteasome degradation	Macroautophagy
Drugs
Diseases
GWAS		Lung cancer ( 28604730)	Hip circumference adjusted for BMI ( 28552196) Metabolite levels ( 23823483)
Interacting Genes		52 interacting genes: APC CALR CASP8AP2 CDC34 CUL1 DAXX DCP2 DZIP3 FADD FBXW11 GABARAP GABARAPL1 GABARAPL2 GRAP HLA-DRB1 IGHG1 IGHV4-31 IKBKB IRF5 IRF8 MAP1LC3A MAP1LC3B MAP1LC3C MNAT1 NIF3L1 PFKP RBCK1 RNF111 RO60 SKP2 SQSTM1 TBK1 TRIM27 TRIM39 TRIM5 TRIM8 TXN2 UBC UBE2C UBE2D1 UBE2D2 UBE2E1 UBE2H UBE2I UBE2L3 UBE2N UBE2V2 UBE2W USP15 USP2 USP4 YWHAZ	19 interacting genes: AMBRA1 ANK2 ANK3 ATG13 ATG4B CUL3 KBTBD6 KBTBD7 LMNB1 MEFV NEDD4 OPTN RB1CC1 SQSTM1 TAX1BP1 TRIM21 ULK1 WDFY3 WDR81
Entrez ID		6737	440738
HPRD ID		00170	14226
Ensembl ID		ENSG00000132109	ENSG00000197769
Uniprot IDs		P19474	Q9BXW4
PDB IDs		2IWG 5JPX 5OLM 6FGA 6S53	2NCN 3VVW 3WAM 3WAP 5DPW
Enriched GO Terms of Interacting Partners?
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