SRPK1 and GABARAPL1

Number of citations of the paper that reports this interaction (PubMedID 23602568)
55

Data Source:
BioGRID (enzymatic study)

		SRPK1	GABARAPL1
Description		SRSF protein kinase 1	GABA type A receptor associated protein like 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Nuclear Matrix	Autophagosome Membrane Intracellular Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body
	Molecular Function	Magnesium Ion Binding RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding Microtubule Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Spliceosomal Complex Assembly Protein Phosphorylation Chromosome Segregation RNA Splicing Regulation Of Gene Expression Viral Process Sperm Chromatin Condensation Intracellular Signal Transduction Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Macroautophagy Autophagosome Maturation
Pathways			Macroautophagy
Drugs
Diseases
GWAS		Antidepressant treatment resistance (> 2 drugs prescribed) ( 30700811)
Interacting Genes		171 interacting genes: ADPRH AHCYL1 ALKBH3 AMMECR1L APEX1 APP ARGLU1 ARHGAP12 ARHGAP26 ASAH1 ASXL1 AURKA AURKC C11orf52 C11orf87 C16orf78 C18orf25 C9orf72 CACNB1 CAMK2D CBX5 CDC42EP3 CDK7 CDKL3 CHEK2 CHERP CHUK CIAO1 CLIC5 CLK1 CLK4 CRHR1 CSAG1 DAW1 DDX47 DHX8 DHX9 DNAJC8 DUSP6 ECM1 EIF3M EPB41L4A EPHA3 ERBB2 ESRRG FAM124A FAM76B FERMT1 FGF12 FHL1 FKBP3 FLOT1 FLT1 GABARAP GABARAPL1 HBS1L HIRIP3 HMGN3 HNRNPA1 IFIT5 IKBKG JHY KCNAB1 KCNN2 KIAA1841 KPNA2 KPTN KRR1 LAMC1 LARP1 LBR LCE3D LIMK1 LINC00312 LUC7L3 MACROH2A1 MAGEB1 MAOB MAP1LC3A MAPK12 MAPK14 MAPKAPK5 MAPT MBNL3 MBP MRPL43 MRPS11 NCK2 NELFE NKAP NOL4L NOP16 NOVA1 NSMCE4A NSRP1 NUDT21 NXT2 OCEL1 ODF3L2 OR6B3 PAK4 PDGFRA PDPK1 PELI1 PELI2 PEX19 PFN1 PHF7 POLR2E PPIA PPIL1 PPIL3 PRM1 PRPF38A PTK2 RBM23 RBM39 RBM8A RBMS2 RIMS4 RNPS1 RPS6KB2 RSRC1 RSRC2 RSRP1 SAFB SCAF11 SEC23B SERPINB10 SETD3 SFMBT1 SLAIN2 SLC4A1AP SNRNP70 SPANXN4 SPATS2 SREK1 SRPK3 SRRM1 SRSF1 SRSF12 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 STAU1 STK26 SUDS3 TAF1B TFEB TNFRSF10C TOP2A TRA2B TRIM65 U2AF1 U2AF2 UBD UBE2E2 USP39 VANGL1 VDR WDR55 YPEL2 YTHDC1 YWHAG ZMYND11 ZNF444 ZNF514 ZRANB2	47 interacting genes: AHNAK2 AMBRA1 ANK2 ATG13 ATG4A ATG4D CALCOCO2 CUL3 DVL2 FUNDC1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAPK15 MEFV NEDD4 OPRK1 OPTN RABGAP1 RABGAP1L RB1CC1 RETREG3 SCYL3 SNCA SQSTM1 SRPK1 SRPK2 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TRIM21 ULK1 VDR WDFY3
Entrez ID		6732	23710
HPRD ID		15992	07601
Ensembl ID		ENSG00000096063	ENSG00000139112
Uniprot IDs		Q96SB4	A0A024RAP5 Q9H0R8
PDB IDs		1WAK 1WBP 3BEG 4WUA 5MXX 5MY8 5NNG 5XV7 6FAD	2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL
Enriched GO Terms of Interacting Partners?
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