SPINK1 and TMPRSS15

Number of citations of the paper that reports this interaction (PubMedID 2093478)
1

		SPINK1	TMPRSS15
Description		serine peptidase inhibitor Kazal type 1	transmembrane serine protease 15
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GO Annotations	Cellular Component	Extracellular Exosome	Brush Border Membrane Integral Component Of Membrane
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding
	Biological Process	Negative Regulation Of Nitric Oxide Mediated Signal Transduction Sperm Capacitation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Acrosome Reaction Negative Regulation Of Calcium Ion Import Negative Regulation Of Serine-type Endopeptidase Activity Regulation Of Store-operated Calcium Entry	Proteolysis Endocytosis
Pathways
Drugs
Diseases		Tropical calcific pancreatitis Hereditary pancreatitis; Hereditary chronic pancreatitis	Enterokinase deficiency
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576) Metabolite levels ( 23823483) Obesity-related traits ( 23251661)	Asthma ( 29273806) Bulimia nervosa ( 23568457) Nucleus accumbens volume in trauma-exposed individuals ( 29187748)
Interacting Genes		5 interacting genes: CTRC ELN NRSN1 TMPRSS15 UBE3A	1 interacting genes: SPINK1
Entrez ID		6690	5651
HPRD ID		01341	05972
Ensembl ID		ENSG00000164266	ENSG00000154646
Uniprot IDs		P00995	P98073
PDB IDs		1CGI 1CGJ 1HPT	4DGJ
Enriched GO Terms of Interacting Partners?
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