SOX11 and POU3F3

Number of citations of the paper that reports this interaction (PubMedID 9632656)
63

Data Source:
HPRD (in vitro)

		SOX11	POU3F3
Description		SRY-box transcription factor 11	POU class 3 homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Transcription Factor Complex	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Homodimerization Activity Sequence-specific DNA Binding HMG Box Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Kidney Development Neural Tube Formation Lens Morphogenesis In Camera-type Eye Outflow Tract Morphogenesis Cardiac Ventricle Formation Noradrenergic Neuron Differentiation Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation Anatomical Structure Morphogenesis Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Oligodendrocyte Development Glial Cell Proliferation Neural Crest Cell Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Spinal Cord Development Glial Cell Development Cell Differentiation Neuron Differentiation Positive Regulation Of BMP Signaling Pathway Positive Regulation Of Hippo Signaling Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Ossification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hormone Secretion Sympathetic Nervous System Development Embryonic Digestive Tract Morphogenesis Embryonic Skeletal System Morphogenesis Negative Regulation Of Lymphocyte Proliferation Positive Regulation Of Neurogenesis Hard Palate Development Soft Palate Development Limb Bud Formation Negative Regulation Of Glial Cell Proliferation Ventricular Septum Morphogenesis Lung Morphogenesis Negative Regulation Of Cell Death Neuroepithelial Cell Differentiation Eyelid Development In Camera-type Eye Somite Development Cornea Development In Camera-type Eye Closure Of Optic Fissure Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Stem Cell Proliferation Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Lens Epithelial Cell Proliferation	Central Nervous System Development Excretion Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Cell Differentiation Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Chemical Homeostasis Metanephric Ascending Thin Limb Development Metanephric Macula Densa Development Metanephric Thick Ascending Limb Development Metanephric Loop Of Henle Development Metanephric DCT Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Automobile speeding propensity ( 30643258) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Chronic kidney disease ( 20383146) Crohn's disease ( 23266558) Diabetic kidney disease ( 26305897) Hip circumference ( 25673412) Intraocular pressure ( 29617998) Obesity in adult survivors of childhood cancer exposed to cranial radiation ( 25963547) Obesity-related traits ( 23251661) Proteinuria and chronic kidney disease ( 26420894) Tuberculosis ( 24057671) Type 2 diabetes ( 31118516)	Body mass index ( 26426971) General risk tolerance (MTAG) ( 30643258) Response to taxane treatment (docetaxel) ( 23006423)
Interacting Genes		3 interacting genes: MTNR1A POU3F2 POU3F3	5 interacting genes: POU3F4 PPP1R15A SOX10 SOX11 SOX8
Entrez ID		6664	5455
HPRD ID		02940	03922
Ensembl ID		ENSG00000176887	ENSG00000198914
Uniprot IDs		P35716	P20264
PDB IDs
Enriched GO Terms of Interacting Partners?
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