SNX2 and FNBP1

Number of citations of the paper that reports this interaction (PubMedID 11438682)
21

Data Source:
HPRD (in vivo, two hybrid)

		SNX2	FNBP1
Description		sorting nexin 2	formin binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Protein-containing Complex	Lysosome Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Cell Cortex Cytoplasmic Vesicle
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Endocytosis Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Lamellipodium Morphogenesis	Endocytosis Membrane Organization
Pathways		Golgi Associated Vesicle Biogenesis	Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) LDL peak particle diameter (total fat intake interaction) ( 26112879) Pediatric autoimmune diseases ( 26301688)
Interacting Genes		20 interacting genes: ACVR1B ACVR2B C1orf122 CSNK2B DUSP10 EGFR FNBP1 INSR LAMC1 LEPR MET NFYC PAK6 PDGFRA PDGFRB SNX1 SNX4 SNX5 SNX6 ZNF202	12 interacting genes: AKAP9 ARHGAP17 CBL CDC42 DNM1 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL
Entrez ID		6643	23048
HPRD ID		09332	10446
Ensembl ID		ENSG00000205302	ENSG00000187239
Uniprot IDs		O60749	B7ZL13 B7ZL14 Q96RU3
PDB IDs			2EFL
Enriched GO Terms of Interacting Partners?
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