SNX1 and FUNDC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SNX1	FUNDC1
Description		sorting nexin 1	FUN14 domain containing 1
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GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Mitochondrial Outer Membrane Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis	Autophagy Of Mitochondrion Response To Hypoxia Response To Organonitrogen Compound Macroautophagy
Pathways			Receptor Mediated Mitophagy
Drugs
Diseases
GWAS			Facial morphology (factor 22) ( 28441456) Personality dimensions ( 18957941)
Interacting Genes		25 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ATXN7 CMTM5 EGFR F2R FUNDC1 HGS INSR LEPR PDGFRB RABAC1 REEP6 RTN3 RTN4 SASH1 SNX2 SNX6 TK1 UFD1 VPS35	15 interacting genes: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MARCHF5 MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1
Entrez ID		6642	139341
HPRD ID		03171	06658
Ensembl ID		ENSG00000028528	ENSG00000069509
Uniprot IDs		Q13596	Q8IVP5
PDB IDs		2I4K 4FZS	2N9X 5GMV
Enriched GO Terms of Interacting Partners?
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