SNRPC and WDR77

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		SNRPC	WDR77
Description		small nuclear ribonucleoprotein polypeptide C	WD repeat domain 77
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GO Annotations	Cellular Component	Commitment Complex Nucleoplasm U1 SnRNP Cajal Body U2-type Prespliceosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome
	Molecular Function	RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Zinc Ion Binding U1 SnRNA Binding Pre-mRNA 5'-splice Site Binding Protein Homodimerization Activity U1 SnRNP Binding	Protein Binding Methyl-CpG Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Spliceosomal SnRNP Assembly MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		mRNA Splicing - Major Pathway	snRNP Assembly RMTs methylate histone arginines
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) HDL cholesterol ( 25961943) Obese vs. thin ( 30677029) Systemic lupus erythematosus ( 24871463)
Interacting Genes		28 interacting genes: AGGF1 DDX42 EWSR1 EXOSC8 FAM168A GOLGA2 HNRNPD HNRNPF HNRNPH2 HNRNPUL1 HSD17B14 ILF3 KHDRBS3 MAGED1 NCAPH2 PSMA3 RBFOX2 RBM11 RBM4 RBPMS RFX6 RNF31 SNRNP70 SPAG8 SS18L1 TLE5 WDR77 WWP2	44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PITRM1 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207
Entrez ID		6631	79084
HPRD ID		04630	14387
Ensembl ID		ENSG00000124562	ENSG00000116455
Uniprot IDs		P09234 Q5TAL4	A0A024R0H7 Q9BQA1
PDB IDs		2VRD 3CW1 4PJO 6ELD 6QX9	4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S
Enriched GO Terms of Interacting Partners?
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