SNRNP70 and HNRNPA2B1

Number of citations of the paper that reports this interaction (PubMedID 29802200)
8

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		SNRNP70	HNRNPA2B1
Description		small nuclear ribonucleoprotein U1 subunit 70	heterogeneous nuclear ribonucleoprotein A2/B1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck U2-type Prespliceosome	Chromosome, Telomeric Region Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Membrane Nuclear Matrix Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding SnRNA Binding U1 SnRNA Binding	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding MiRNA Binding Single-stranded Telomeric DNA Binding Pre-mRNA Intronic Binding G-rich Strand Telomeric DNA Binding N6-methyladenosine-containing RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of ATPase Activity Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome MRNA Processing MRNA Export From Nucleus Viral Process RNA Metabolic Process Primary MiRNA Processing Interleukin-12-mediated Signaling Pathway G-quadruplex DNA Unwinding Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Transport Regulation Of RNA Metabolic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Telomerase RNA Reverse Transcriptase Activity MiRNA Transport
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Copper Artenimol
Diseases
GWAS		Systolic blood pressure ( 30224653)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		41 interacting genes: APP ARSF CDKL3 CEP63 CHERP CRP CTDP1 DDX17 GEMIN2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2	19 interacting genes: CDKN2A CSNK2A1 CSNK2B ERG ESR1 H3-4 HIPK3 HNRNPL HSPB1 LIG4 MAP4K2 MCPH1 NR4A1 SNRNP70 SREK1 TTF2 VHL YAE1 ZMYM2
Entrez ID		6625	3181
HPRD ID		01617	02526
Ensembl ID		ENSG00000104852	ENSG00000122566
Uniprot IDs		A0A024QZD5 P08621 Q9UFS1	P22626
PDB IDs		2L5I 2L5J 3CW1 3PGW 4PJO 4PKD 6QX9	1X4B 5EN1 5HO4 5WWE 5WWF 5WWG
Enriched GO Terms of Interacting Partners?
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