UPF3B and MCRS1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UPF3B	MCRS1
Description		UPF3B regulator of nonsense mediated mRNA decay	microspherule protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Centriolar Satellite Exon-exon Junction Complex	Histone Acetyltransferase Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Polysome Dendrite Ino80 Complex Perikaryon NSL Complex MLL1 Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Structural Constituent Of Nuclear Pore	G-quadruplex RNA Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific)
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Positive Regulation Of Translation	DNA Repair DNA Recombination Cellular Protein Modification Process Viral Process Protein Deubiquitination Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Localization To Nucleolus
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	HATs acetylate histones UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases		Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS
Interacting Genes		13 interacting genes: EIF4A3 EIF6 EXOSC4 HBB MAGOH MCRS1 RBBP6 RBM8A SRPK2 TTC19 UPF1 UPF2 XRN1	31 interacting genes: BLM CCDC85B CEP44 DAXX DVL2 FXR2 GCC1 GPBP1 IKZF1 KDM1A KIAA1958 KXD1 LIG4 LSM6 MAGEA11 MED4 NOP2 PBX2 PHC2 PINX1 PRMT5 PTEN RALYL SUV39H1 TERT TRIM37 UPF3B USHBP1 WASHC3 WBP11 ZBTB22
Entrez ID		65109	10445
HPRD ID		02247	11298
Ensembl ID		ENSG00000125351	ENSG00000187778
Uniprot IDs		Q9BZI7	A0A024R134 Q96EZ8
PDB IDs		1UW4 2XB2
Enriched GO Terms of Interacting Partners?
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