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SKI and NFIX
Number of citations of the paper that reports this interaction (PubMedID
9380514
)
15
Data Source:
BioGRID
(pull down, genetic interference)
HPRD
(in vitro)
SKI
NFIX
Description
SKI proto-oncogene
nuclear factor I X
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Centrosome
Nuclear Body
PML Body
Transcriptional Repressor Complex
Protein-containing Complex
Nuclear Chromatin
Nucleus
Molecular Function
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Corepressor Activity
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Protein Domain Specific Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
SMAD Binding
Histone Deacetylase Inhibitor Activity
Repressing Transcription Factor Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Neural Tube Closure
Lens Morphogenesis In Camera-type Eye
Transcription, DNA-templated
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Cell Proliferation
Anterior/posterior Axis Specification
Negative Regulation Of Schwann Cell Proliferation
Myotube Differentiation
Olfactory Bulb Development
Myelination In Peripheral Nervous System
Positive Regulation Of Wnt Signaling Pathway
Embryonic Limb Morphogenesis
BMP Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of BMP Signaling Pathway
Negative Regulation Of Histone Deacetylation
Negative Regulation Of Activin Receptor Signaling Pathway
Somatic Stem Cell Population Maintenance
Camera-type Eye Development
Positive Regulation Of DNA Binding
Nose Morphogenesis
Negative Regulation Of Osteoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Fibroblast Proliferation
Camera-type Eye Morphogenesis
Skeletal Muscle Fiber Development
Cell Motility
Roof Of Mouth Development
Retina Development In Camera-type Eye
Face Morphogenesis
Bone Morphogenesis
SMAD Protein Signal Transduction
Negative Regulation Of Transcription By RNA Polymerase II
DNA Replication
Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Signaling by BMP
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Coronary artery disease (
29212778
)
Platelet distribution width (
27863252
)
PR interval (
30046033
)
Systolic blood pressure (
30224653
)
Urate levels (
31578528
)
Bipolar disorder (
28115744
)
Body mass index (
25673413
)
Clozapine-induced agranulocytosis (
25187353
)
Granulocyte percentage of myeloid white cells (
27863252
)
Heel bone mineral density (
30598549
)
Intelligence (MTAG) (
29326435
)
Monocyte count (
27863252
)
Monocyte percentage of white cells (
27863252
)
Interacting Genes
20 interacting genes:
AKT1
GLI2
GLI3
HIPK2
JUN
MECP2
MYB
NCOR1
NFIX
PML
SIN3A
SKIL
SMAD1
SMAD2
SMAD3
SMAD4
SNW1
SPI1
TGFBR1
TRIM28
7 interacting genes:
JMJD6
NFIB
PIR
QRICH1
RFX1
SKI
ZNF614
Entrez ID
6497
4784
HPRD ID
01271
01234
Ensembl ID
ENSG00000157933
ENSG00000008441
Uniprot IDs
P12755
B4DHW2
D2DXM9
Q14938
PDB IDs
1MR1
1SBX
5XOD
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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