AIDA and PINX1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		AIDA	PINX1
Description		axin interactor, dorsalization associated	PIN2 (TERF1) interacting telomerase inhibitor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Membrane	Nuclear Chromosome Kinetochore Condensed Chromosome Kinetochore Chromosome, Telomeric Region Nuclear Chromosome, Telomeric Region Cell Nucleoplasm Nucleolus Spindle
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding	Protein Binding Telomerase Inhibitor Activity Protein-containing Complex Binding Telomerase RNA Binding
	Biological Process	Dorsal/ventral Pattern Formation Negative Regulation Of Protein Complex Assembly Negative Regulation Of JUN Kinase Activity Negative Regulation Of JNK Cascade Determination Of Ventral Identity	Telomere Maintenance Via Telomerase Mitotic Metaphase Plate Congression Negative Regulation Of Cell Proliferation Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Negative Regulation Of Telomerase Activity Protein Localization To Chromosome, Telomeric Region Protein Localization To Nucleolus Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Telomeric DNA Binding Positive Regulation Of Protein Localization To Nucleolus
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Adventurousness ( 30643258) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder ( 30804558) Carotid intima media thickness ( 30510157 21909108) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Gut microbiota (beta diversity) ( 27723756) Lymphocyte counts ( 27863252) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (calcium channel blockers) ( 31015401) Retinal vascular caliber ( 21060863) Systemic lupus erythematosus ( 26316170) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Triglyceride levels ( 28334899) Triglycerides ( 24097068 30275531 20686565) Type 2 diabetes ( 30054458) White blood cell count ( 27863252)
Interacting Genes		6 interacting genes: APP FAM118A LNX1 PINX1 PLEKHF2 ZDHHC17	10 interacting genes: AIDA APP CACYBP GABPA MCRS1 MPZ PAFAH1B2 TERF1 TERT TP63
Entrez ID		64853	54984
HPRD ID		07798	05934
Ensembl ID		ENSG00000186063	ENSG00000254093
Uniprot IDs		Q96BJ3	Q96BK5
PDB IDs
Enriched GO Terms of Interacting Partners?
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