SIAH2 and HIPK2

  • Number of citations of the paper that reports this interaction (PubMedID 19043406)
  • 42
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study)

SIAH2

HIPK2

Description siah E3 ubiquitin protein ligase 2 homeodomain interacting protein kinase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
  • Systolic blood pressure ( 28135244)
Interacting Genes 43 interacting genes: AFF1 AKR1C3 ATN1 CACYBP CCBE1 CHEK2 DCC DYRK2 EEF1D EGLN3 HIPK2 HIPK3 MYD88 NRF1 OPRM1 PEG10 PEG3 PIAS2 PIAS3 PML POU2AF1 PSMD4 RBBP8 SETD2 SNCA SNCAIP SPRY2 STAT3 SYP TINF2 TP53BP2 TPX2 TRAF2 UBE2D1 UBE2D2 UBE2D3 UBE2I UBE2L6 UBE2N UBE2V2 USP13 USP19 VAV1 54 interacting genes: AATF ABL1 BTRC CBX3 CHMP4B CREBBP CUL1 CXCL1 DAXX DDX39A DDX39B EP300 FBXW7 H2BC21 HMGA1 KAT2B MAP3K7 MBP MDM2 MECP2 MKNK1 MYB MYBL1 NKX2-1 NKX2-5 NKX3-1 NLK PARP1 PAX6 PML PTCH1 RANBP9 RUNX1 SCAP SENP1 SIAH1 SIAH2 SIRT1 SKI SMAD1 SMAD2 SMAD3 SP100 SUMO1 SUMO2 SUMO3 TP53 TP53INP1 TP63 TP73 TRADD UBE2I WSB1 ZBTB4
Entrez ID 6478 28996
HPRD ID 03737 06039
Ensembl ID ENSG00000181788 ENSG00000064393
Uniprot IDs O43255 Q9H2X6
PDB IDs 5H9M 6P5S
Enriched GO Terms of Interacting Partners?
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