CLEC7A and BNIP3L

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		CLEC7A	BNIP3L
Description		C-type lectin domain containing 7A	BCL2 interacting protein 3 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Cytosol Integral Component Of Membrane Nuclear Speck Intrinsic Component Of Membrane
	Molecular Function	(1->3)-beta-D-glucan Binding Protein Binding Carbohydrate Binding Pattern Recognition Receptor Activity MHC Protein Binding Metal Ion Binding	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Phagocytosis, Recognition Inflammatory Response Cell Recognition Positive Regulation Of Cell Proliferation Carbohydrate Mediated Signaling Positive Regulation Of Gene Expression Detection Of Fungus Positive Regulation Of Cell Migration Positive Regulation Of Protein Complex Assembly Detection Of Molecule Of Fungal Origin Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Superoxide Anion Generation T Cell Activation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Defense Response To Protozoan Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Interferon-gamma Biosynthetic Process Positive Regulation Of Interleukin-10 Biosynthetic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Positive Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Positive Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Interleukin-8 Biosynthetic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Phagocytosis Positive Regulation Of Lymphocyte Activation Positive Regulation Of Killing Of Cells Of Other Organism Positive Regulation Of Respiratory Burst Cellular Response To Molecule Of Fungal Origin Positive Regulation Of Monocyte Chemotactic Protein-1 Production Positive Regulation Of Wound Healing Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Cell Maturation	Negative Regulation Of Mitochondrial Membrane Potential Viral Process Positive Regulation Of Macroautophagy Mitochondrial Protein Catabolic Process Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Defense Response To Virus Negative Regulation Of Cell Death Cellular Response To Hypoxia Mitochondrial Outer Membrane Permeabilization Regulation Of Autophagy Of Mitochondrion Regulation Of Protein Targeting To Mitochondrion
Pathways		CLEC7A (Dectin-1) signaling CLEC7A (Dectin-1) signaling	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Drugs
Diseases		Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS			Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Red cell distribution width ( 27863252) Schizophrenia ( 28991256 30285260)
Interacting Genes		19 interacting genes: ADAM33 AIP BNIP3 BNIP3L CALM3 FAM3A HSPD1 IL1RL1 JAGN1 KTN1 NINJ2 OCLN PTTG1IP RANBP9 RHOU SMIM3 SYNE4 TMEM79 TMPRSS4	26 interacting genes: ADIPOQ BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 DOK5 DUSP3 ECM1 EWSR1 FATE1 GBP2 GNB5 KLHL23 LDLRAD1 LMNA MAP1LC3A NGFR RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11
Entrez ID		64581	665
HPRD ID		08396	07288
Ensembl ID		ENSG00000172243	ENSG00000104765
Uniprot IDs		A0A024RAN9 A0A0S2Z5Q1 Q68D78 Q9BXN2	O60238 Q6IBV1
PDB IDs
Enriched GO Terms of Interacting Partners?
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