CENPK and CENPH

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		CENPK	CENPH
Description		centromere protein K	centromere protein H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Inner Kinetochore Nucleoplasm Cytosol	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Protein Binding	Protein Binding Kinetochore Binding
	Biological Process	Mitotic Sister Chromatid Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly	Mitotic Spindle Organization Chromosome Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Diverticular disease ( 30177863)
Interacting Genes		6 interacting genes: AP1G2 CENPH HSPB1 MRFAP1L1 PCBD2 SOX6	5 interacting genes: CENPK KIF2C MTAP NDC80 NUF2
Entrez ID		64105	64946
HPRD ID		13323	12029
Ensembl ID		ENSG00000123219	ENSG00000153044
Uniprot IDs		D6RHD3 Q9BS16	A0A0S2Z5T0 Q9H3R5
PDB IDs
Enriched GO Terms of Interacting Partners?
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