PRDM1 and EXOSC3

PRDM1

EXOSC3

Description PR/SET domain 1 exosome component 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
  • Carboplatin disposition in epthelial ovarian cancer ( 29367611)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 21102463)
  • Diastolic blood pressure ( 30224653)
  • Monobrow ( 27182965)
  • Multiple myeloma ( 27363682)
  • Response to (pegylated) interferon in HBeAG-positive hepatitis B ( 30715261)
  • Sjögren's syndrome ( 24097067)
  • Systemic lupus erythematosus ( 27399966 23273568 26502338 28714469 19838193 19838195)
  • Systemic sclerosis ( 28314753)
Interacting Genes 11 interacting genes: ATXN1 EXOSC3 H1-1 H3C15 IKZF3 IRF4 KDM1A PIAS1 TLE1 TLE2 TLE5 10 interacting genes: APP ATP5F1D CDK5RAP1 EXOSC4 EXOSC5 EXOSC9 KHSRP MPHOSPH6 PRDM1 PRDX1
Entrez ID 639 51010
HPRD ID 04572 16220
Ensembl ID ENSG00000057657 ENSG00000107371
Uniprot IDs A0A3B3IU23 B4DW27 O75626 Q5T4E8 Q9NQT5 Q9NYS3
PDB IDs 3DAL 2NN6 6D6Q 6D6R 6H25
Enriched GO Terms of Interacting Partners?
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