CCL25 and CCR9

Number of citations of the paper that reports this interaction (PubMedID 10229797)
37

Data Source:
HPRD (in vitro, in vivo)

		CCL25	CCR9
Description		C-C motif chemokine ligand 25	C-C motif chemokine receptor 9
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cell Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	Hormone Activity Protein Binding Chemokine Activity CCR10 Chemokine Receptor Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding	Chemokine Receptor Activity C-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Negative Regulation Of Leukocyte Tethering Or Rolling	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			CCX282
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399) Sphingolipid levels ( 26068415)	Celiac disease ( 20190752)
Interacting Genes		4 interacting genes: ACKR2 ACKR4 CCR10 CCR9	1 interacting genes: CCL25
Entrez ID		6370	10803
HPRD ID		03976	09200
Ensembl ID		ENSG00000131142	ENSG00000173585
Uniprot IDs		O15444	B2R734 P51686
PDB IDs			5LWE
Enriched GO Terms of Interacting Partners?
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