CCL19 and CXCL13

Number of citations of the paper that reports this interaction (PubMedID 16678487)
25

Data Source:
HPRD (in vivo, in vitro)

		CCL19	CXCL13
Description		C-C motif chemokine ligand 19	C-X-C motif chemokine ligand 13
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell	Extracellular Region Extracellular Space Cell
	Molecular Function	Chemokine Activity CCR7 Chemokine Receptor Binding CCR10 Chemokine Receptor Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding	Chemokine Activity Heparin Binding Fibroblast Growth Factor Binding CXCR5 Chemokine Receptor Binding CCR10 Chemokine Receptor Binding CXCR Chemokine Receptor Binding Receptor Ligand Activity CXCR3 Chemokine Receptor Binding
	Biological Process	Establishment Of T Cell Polarity Immunological Synapse Formation Dendritic Cell Chemotaxis Myeloid Dendritic Cell Chemotaxis Monocyte Chemotaxis Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Cellular Calcium Ion Homeostasis Inflammatory Response Immune Response Cell Communication G Protein-coupled Receptor Signaling Pathway Activation Of JUN Kinase Activity Response To Virus Positive Regulation Of Glycoprotein Biosynthetic Process Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis T Cell Costimulation Positive Regulation Of Interleukin-12 Production Positive Regulation Of Tumor Necrosis Factor Production Response To Prostaglandin E Positive Regulation Of T Cell Proliferation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of GTPase Activity Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of T-helper 1 Cell Differentiation Positive Regulation Of Endocytosis Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Lymphocyte Chemotaxis Positive Regulation Of Receptor-mediated Endocytosis Cell Maturation Positive Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of Chemotaxis Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Protein Kinase B Signaling Regulation Of Cell Projection Assembly Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Response To Nitric Oxide Interleukin-12 Secretion Positive Regulation Of Neutrophil Chemotaxis Mature Conventional Dendritic Cell Differentiation Cellular Response To Virus Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Cell Motility Positive Regulation Of Dendritic Cell Dendrite Assembly Negative Regulation Of Dendritic Cell Apoptotic Process	Germinal Center Formation Lymphocyte Chemotaxis Across High Endothelial Venule Chronic Inflammatory Response Regulation Of Humoral Immune Response Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Leukocyte Chemotaxis Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin B Cell Chemotaxis Endothelial Cell Chemotaxis To Fibroblast Growth Factor Defense Response To Bacterium Regulation Of Angiogenesis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Activation Of GTPase Activity Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Rheumatoid arthritis ( 30423114 24390342)	Cardiac Troponin-T levels ( 23247143) Diffusing capacity of carbon monoxide ( 30694715) Tonsillectomy ( 27182965 28928442) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		6 interacting genes: ACKR2 ACKR4 CCL22 CCR10 CCR7 CXCL13	8 interacting genes: ACKR4 CCL19 CCL21 CCR10 CXCR3 CXCR5 EEF1G FGF2
Entrez ID		6363	10563
HPRD ID		03750	05513
Ensembl ID		ENSG00000172724	ENSG00000156234
Uniprot IDs		Q6IBD6 Q99731	O43927 Q53X90
PDB IDs		2MP1	4ZAI 5CBA 5CBE
Enriched GO Terms of Interacting Partners?
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