SAFB and HNRNPA1

Number of citations of the paper that reports this interaction (PubMedID 10212141)
39

Data Source:
HPRD (in vitro)

		SAFB	HNRNPA1
Description		scaffold attachment factor B	heterogeneous nuclear ribonucleoprotein A1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Binding Protein Binding Sequence-specific DNA Binding	Single-stranded DNA Binding RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding MiRNA Binding Pre-mRNA Binding Telomeric Repeat-containing RNA Binding G-rich Strand Telomeric DNA Binding
	Biological Process	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Hormone Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Processing	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus Fibroblast Growth Factor Receptor Signaling Pathway Viral Process RNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Glucose Starvation MRNA Transport Nuclear Export Import Into Nucleus Regulation Of RNA Metabolic Process Cellular Response To Sodium Arsenite
Pathways		SUMOylation of transcription cofactors	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: ABHD16A CDC37 CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R MAP1LC3B NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRPK2 SRSF9 TAF15 TJP2	40 interacting genes: ABHD16A APP BCL2L1 CLK1 ERG ESR1 FEN1 H3-4 H3C1 HIPK3 HMGA1 HNRNPH3 KHSRP NFKBIA NR0B2 NR3C1 PABPN1 PHYHIP PPIL1 PRKDC PRMT1 PRMT2 PRMT3 PRRC2A RNF14 RPL21 RPS6KB2 SAFB SNRNP200 SREK1 SRPK1 SRPK2 SUFU TFEC TNPO1 TRA2B TRAF6 TTF2 XIAP XRN1
Entrez ID		6294	3178
HPRD ID		04205	01242
Ensembl ID		ENSG00000160633	ENSG00000135486
Uniprot IDs		B7Z2F6 B7ZLP5 Q15424	A0A024RAZ7 A0A024RB53 P09651
PDB IDs			1HA1 1L3K 1PGZ 1PO6 1U1K 1U1L 1U1M 1U1N 1U1O 1U1P 1U1Q 1U1R 1UP1 2H4M 2LYV 2UP1 4YOE 5MPG 5MPL 5ZGD 5ZGL 6BXX 6DCL 6J60
Enriched GO Terms of Interacting Partners?
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