RPS15A and ELF5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		RPS15A	ELF5
Description		ribosomal protein S15a	E74 like ETS transcription factor 5
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Positive Regulation Of Cell Proliferation Response To Virus Viral Transcription Positive Regulation Of Cell Cycle	Ectodermal Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Cell Differentiation Somatic Stem Cell Population Maintenance Negative Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Mammary Gland Epithelial Cell Differentiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Blood protein levels ( 29875488)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Blood protein levels ( 28240269) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: CALM1 CDC37 DDX39B ELF5 EWSR1 FBXO7 PTEN RHOU UBE3A VHL	8 interacting genes: ACTR2 FRZB NFE2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4
Entrez ID		6210	2001
HPRD ID		04723	05525
Ensembl ID		ENSG00000134419	ENSG00000135374
Uniprot IDs		B2R4W8 P62244	A0A087X1W9 A8K443 Q9UKW6
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	1WWX
Enriched GO Terms of Interacting Partners?
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