RPS6 and OLFM2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		RPS6	OLFM2
Description		ribosomal protein S6	olfactomedin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Endoplasmic Reticulum Cytosol Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit Dendrite Cytoplasmic Ribonucleoprotein Granule Cell Body Ribonucleoprotein Complex	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cell Junction AMPA Glutamate Receptor Complex Glutamatergic Synapse Extrinsic Component Of Synaptic Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Protein Kinase Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription TOR Signaling Ribosomal Small Subunit Biogenesis Glucose Homeostasis Positive Regulation Of Apoptotic Process	Visual Perception Locomotory Behavior Protein Secretion Positive Regulation Of Smooth Muscle Cell Differentiation Regulation Of Vascular Smooth Muscle Cell Dedifferentiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation mTORC1-mediated signalling SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Artenimol
Diseases
GWAS		Total cholesterol levels ( 29083408)	Blood protein levels ( 30072576) Menarche (age at onset) ( 27182965 21102462 25231870) Sleep duration ( 30531941)
Interacting Genes		13 interacting genes: ATF4 FRS2 NDRG1 OLFM2 PAK2 PLA2G12A PRKACB PRKCSH PTEN RPS6KB1 RPS6KB2 STAU1 UPF2	11 interacting genes: BLOC1S6 EIF1 FANCF GNB5 KRTAP10-3 NBAS PKM ROBO2 RPS6 SRSF5 ST13
Entrez ID		6194	93145
HPRD ID		01592	10127
Ensembl ID		ENSG00000137154	ENSG00000105088
Uniprot IDs		A2A3R6 P62753	K7EIS8 O95897
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6F4P 6F4Q 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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