RPS3A and CHN1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RPS3A	CHN1
Description		ribosomal protein S3A	chimerin 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Cytosolic Small Ribosomal Subunit Synapse Extracellular Exosome Ribonucleoprotein Complex	Cytosol
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding MRNA 5'-UTR Binding	SH3/SH2 Adaptor Activity GTPase Activator Activity Protein Binding Metal Ion Binding Ephrin Receptor Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Cell Differentiation Negative Regulation Of Apoptotic Process	Motor Neuron Axon Guidance Positive Regulation Of Signal Transduction Intracellular Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Rho GTPase cycle
Drugs
Diseases			Duane retraction syndrome
GWAS		HDL cholesterol ( 20686565)	Post bronchodilator FEV1 ( 26634245)
Interacting Genes		17 interacting genes: ATF7IP C11orf49 CCDC50 CHN1 CREB3 DDIT3 EDEM2 FANCC HGS HSP90AA1 NEDD4 PARP1 SAP18 SOD2 TOE1 UBE2I VDAC2	12 interacting genes: ACVR1 BMPR1B CDK5 CDK5R1 ERBB2 GTF3C1 HEMK1 MAPK8IP2 NCK2 RAC1 RPS3A TGFBR1
Entrez ID		6189	1123
HPRD ID		01606	00319
Ensembl ID		ENSG00000145425	ENSG00000128656
Uniprot IDs		B7Z3M5 P61247	P15882
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	2OSA 3CXL
Enriched GO Terms of Interacting Partners?
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