MRPL12 and POLR1D

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MRPL12	POLR1D
Description		mitochondrial ribosomal protein L12	RNA polymerase I and III subunit D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit	RNA Polymerase III Complex RNA Polymerase I Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity
	Biological Process	Mitochondrial Transcription Positive Regulation Of Transcription, DNA-templated Mitochondrial Translational Elongation Mitochondrial Translational Termination	Transcription By RNA Polymerase I Transcription By RNA Polymerase III
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases			Treacher Collins syndrome
GWAS		LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)	Body mass index ( 26426971)
Interacting Genes		5 interacting genes: COX6A2 OLIG1 POLR1D RARG TMEM51	15 interacting genes: CD3EAP CDC25A CRKL DDIT3 DNAJB4 DNAJB6 E2F4 GRB2 HAX1 MAGEA11 MRPL12 NFKBIB NR3C1 POLR1C PXN
Entrez ID		6182	51082
HPRD ID		03849	17877
Ensembl ID		ENSG00000262814	ENSG00000186184
Uniprot IDs		P52815	A0A087WTY1 P0DPB5 P0DPB6
PDB IDs
Enriched GO Terms of Interacting Partners?
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