RPLP1 and CDK2AP2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		RPLP1	CDK2AP2
Description		ribosomal protein lateral stalk subunit P1	cyclin dependent kinase 2 associated protein 2
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GO Annotations	Cellular Component	Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit	Nucleus Cytoplasm Microtubule
	Molecular Function	Structural Constituent Of Ribosome Protein Binding Protein Kinase Activator Activity Ribonucleoprotein Complex Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation Translational Elongation Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Activation Of Protein Kinase Activity	Regulation Of Microtubule Cytoskeleton Organization Regulation Of Stem Cell Division Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464 24292274 23770605) Male-pattern baldness ( 27182965) Non-response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		35 interacting genes: ANKRD13B ARF6 ASCC2 ATP5MF BRD7 C11orf58 C15orf39 CDIPT CDK2AP2 CLIC1 CSNK2A1 EEF1A1 GEMIN7 GSK3B LRIF1 MAP1LC3B MPC2 NSF NUDT21 NUDT3 PDCD4 PFDN1 PPP2CB PTN RCHY1 RPA2 RPLP2 RPS6KA6 SAT1 SGO1 TAB1 TPT1 TUBB2A UBE2D3 XRCC6	17 interacting genes: A2M APP CDK2AP1 DBN1 EED EEF1G HSF4 IKZF1 MBTPS1 MRFAP1L1 PYCR1 RCC1 RPLP1 TRA2A WARS1 YIF1A ZBTB48
Entrez ID		6176	10263
HPRD ID		01611	13242
Ensembl ID		ENSG00000137818	ENSG00000167797
Uniprot IDs		A0A024R608 P05386	O75956 Q6IAV4
PDB IDs		2LBF 4BEH 4V6X	2M1L
Enriched GO Terms of Interacting Partners?
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