RPL8 and DUSP23

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		RPL8	DUSP23
Description		ribosomal protein L8	dual specificity phosphatase 23
Image
GO Annotations	Cellular Component	Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Postsynapse	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Binding Structural Constituent Of Ribosome RRNA Binding	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Alpha-Hydroxy-Beta-Phenyl-Propionic Acid Anisomycin Puromycin	4-Nitrophenyl Phosphate
Diseases
GWAS		Blood metabolite levels ( 26401656) Logical memory (immediate recall) in normal cognition ( 29274321)	Bone mineral density (Ward's triangle area) ( 27397699) C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Interacting Genes		13 interacting genes: ARIH2 ARL15 C11orf49 CHDH DPH3 DUSP23 FGFR3 IL7R MINDY3 NUDT3 ST3GAL3 UBE2I UPF2	24 interacting genes: ASB13 CCDC186 CEP126 DBI DBN1 DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 MKRN1 MRPL20 MTFR1 NIF3L1 PRDX4 RPL8 RUFY2 SHC1 SMPD1 TMOD3 TUBA1A ZNF746
Entrez ID		6132	54935
HPRD ID		16044	07908
Ensembl ID		ENSG00000161016	ENSG00000158716
Uniprot IDs		P62917	A0A140VJI5 Q9BVJ7
PDB IDs		4CCM 4CCN 4CCO 4UG0 4V6X 4Y3O 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	2IMG 4ERC
Enriched GO Terms of Interacting Partners?
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