PAPPA2 and SMAD4

  • Number of citations of the paper that reports this interaction (PubMedID 15231748)
  • 85
  • Data Source:
  • HPRD (two hybrid)

PAPPA2

SMAD4

Description pappalysin 2 SMAD family member 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Automobile speeding propensity ( 30643258)
  • Birth weight ( 31043758)
  • Body mass index ( 26426971)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273)
  • Height ( 20881960 25429064 31562340)
  • Offspring birth weight ( 31043758)
  • Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407)
  • Pulse pressure ( 27841878 30578418)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 5 interacting genes: ATF7IP IGFBP3 IGFBP5 SMAD4 ZNF512B 189 interacting genes: ACVR1B AKT1 AP2B1 APBB2 AR ARFRP1 ARL5B ATF2 ATF7IP BCAS3 BEX1 BRCA1 BTRC CAMK2G CD59 CEBPA CEBPB CEBPD CHEK1 CITED1 CNKSR1 COPS5 CREBBP CSH1 CSH2 CTCF CTNNB1 CYFIP2 DACH1 DCP1A DCP1B DKK3 DLX1 DNAJB2 DNMT3L DVL1 ECSIT EEF1A1 EID2 EIF2AK4 EP300 ERBIN ESR1 ESR2 EWSR1 FBLN1 FBXO30 FBXO34 FHL2 FHL3 FN1 FOXG1 FOXH1 FOXO1 FOXO3 FOXO4 FSTL3 GATA2 GLI3 GPNMB GREB1 HDGF HDLBP HMG20A HNF4A HOXA9 HOXC8 HYAL2 IL24 ITK JUN JUNB JUND LEF1 LMO4 LRATD2 LYPD3 MAPK1 MAPK13 MAX MDM4 MECOM MEF2A MEX3B MYOD1 NAT8 NEK6 NELFCD NFIA NKX3-2 NOTCH4 NR0B2 NRAS NUAK2 NUP214 OTUB1 PAK1 PAPPA2 PARD3 PBK PIAS1 PIAS2 PIAS3 PIAS4 PLG PLK4 PRKAR1B PRKAR2A PRPF40A PSG2 PSG9 PSMD11 RAB13 RAB25 RAB2B RAB34 RAB38 RAB3B RAC2 RALA RASD2 RASL12 RASSF5 RBL1 RELA RFX1 RHEBL1 RHOD RHOG RHOJ RIPK2 RMND5B RPL28 RPS27A RRAS2 RSPH14 S100A14 SASH3 SERPINA1 SERPINB5 SKI SKIL SKP2 SMAD1 SMAD2 SMAD3 SMAD5 SMAD7 SMAD9 SNIP1 SNRNP70 SNW1 SOX12 SP1 SPTBN1 SQSTM1 STK11IP STK35 STUB1 TCTA TDG TENM3 TFE3 TGFBR1 TGFBR2 TGFBRAP1 THRSP TIAF1 TM9SF2 TOB1 TRAP1 TSSK3 UBA52 UBB UBE2I UBE2L3 UBE2Z UHRF2 USB1 USP4 USP9X WWOX XPO5 ZBED5 ZBTB7A ZMYM2 ZNF423 ZNF521 ZNF8
Entrez ID 60676 4089
HPRD ID 10156 02995
Ensembl ID ENSG00000116183 ENSG00000141646
Uniprot IDs Q9BXP8 A0A024R274 Q13485
PDB IDs 1DD1 1G88 1MR1 1U7F 1U7V 1YGS 5C4V 5MEY 5MEZ 5MF0 5UWU
Enriched GO Terms of Interacting Partners?
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