EXOC4 and DLGAP4

Number of citations of the paper that reports this interaction (PubMedID 12675619)
13

Data Source:
HPRD (in vitro, in vivo)

		EXOC4	DLGAP4
Description		exocyst complex component 4	DLG associated protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Cell Cytoplasm Cytosol Plasma Membrane Microvillus Membrane Growth Cone Membrane Myelin Sheath Abaxonal Region Synapse Flemming Body	Plasma Membrane Neuromuscular Junction Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding Ral GTPase Binding PDZ Domain Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Protein Targeting To Membrane Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Chemical Synaptic Transmission Regulation Of Macroautophagy Paraxial Mesoderm Formation Vesicle Tethering Involved In Exocytosis	Signaling
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Food allergy ( 29030101) General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Moderate to vigorous physical activity levels ( 29899525) Mood instability ( 31168069) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) QT interval ( 29213071) Response to selective serotonin reuptake inhibitors in depression ( 30034349) Tonometry ( 17903302) Vigorous physical activity ( 29899525)
Interacting Genes		9 interacting genes: BIRC6 CEP63 DISC1 DLG3 DLG4 DLGAP4 EXOC7 GRIN2B RALA	15 interacting genes: BIN1 DLG1 DLG3 DLG4 EXOC4 GRIN1 GRIN2D PLP2 PPP1R1B SH3GL2 SHANK2 SHANK3 SORBS2 SYNGAP1 UBC
Entrez ID		60412	22839
HPRD ID		12185	16826
Ensembl ID		ENSG00000131558	ENSG00000080845
Uniprot IDs		Q6NX51 Q96A65	A0A0B4J2C2 Q9Y2H0
PDB IDs
Enriched GO Terms of Interacting Partners?
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