RHAG and CD47

Number of citations of the paper that reports this interaction (PubMedID 8563755)
11

Data Source:
HPRD (in vivo)

		RHAG	CD47
Description		Rh associated glycoprotein	CD47 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Ammonium Transmembrane Transporter Activity Leak Channel Activity Ankyrin Binding Carbon Dioxide Transmembrane Transporter Activity	Protein Binding Thrombospondin Receptor Activity Protein Binding Involved In Heterotypic Cell-cell Adhesion Cell-cell Adhesion Mediator Activity
	Biological Process	Cellular Ion Homeostasis Carbon Dioxide Transport Monovalent Inorganic Cation Transport Ammonium Transport Bicarbonate Transport Carbon Dioxide Transmembrane Transport Erythrocyte Development Multicellular Organismal Iron Ion Homeostasis Ammonium Transmembrane Transport	Inflammatory Response Integrin-mediated Signaling Pathway Opsonization Positive Regulation Of Cell Proliferation Response To Bacterium Cell Migration Positive Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Regulation Of Interferon-gamma Production Regulation Of Interleukin-10 Production Regulation Of Interleukin-12 Production Regulation Of Interleukin-6 Production Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion Monocyte Extravasation Neutrophil Degranulation Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Positive Regulation Of T Cell Activation Leukocyte Migration Positive Regulation Of Stress Fiber Assembly Monocyte Aggregation Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Interleukin-12 Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Pathways		Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Rhesus glycoproteins mediate ammonium transport. Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN)	Cell surface interactions at the vascular wall Integrin cell surface interactions Signal regulatory protein family interactions Signal regulatory protein family interactions Neutrophil degranulation
Drugs
Diseases		Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS		Alcohol dependence ( 26365420)	Bipolar disorder ( 31043756) Body mass index ( 25673413) Regular attendance at a religious group ( 29970889)
Interacting Genes		6 interacting genes: ANK1 CD47 GYPB ICAM4 LMNA SLC4A1	12 interacting genes: BNIP3 EPB42 FAS GNAI1 ITGAV P2RY2 PTK2 RHAG SIRPA SYNE4 THBS1 UBQLN1
Entrez ID		6005	961
HPRD ID		01582	03017
Ensembl ID		ENSG00000112077	ENSG00000196776
Uniprot IDs		Q02094 Q96E98	A0A0A1TSG4 Q08722
PDB IDs			2JJS 2JJT 2VSC 4CMM 4KJY 5IWL 5TZ2 5TZT 5TZU
Enriched GO Terms of Interacting Partners?
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