RFC3 and MESD

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		RFC3	MESD
Description		replication factor C subunit 3	mesoderm development LRP chaperone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor C Complex Ctf18 RFC-like Complex	Cellular_component Endoplasmic Reticulum Plasma Membrane
	Molecular Function	DNA Binding DNA Clamp Loader Activity Protein Binding ATPase Activity Single-stranded DNA-dependent ATP-dependent DNA Helicase Activity	Molecular_function Identical Protein Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	DNA Synthesis Involved In DNA Repair DNA Replication DNA-dependent DNA Replication DNA Strand Elongation Involved In DNA Replication DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Gap Filling Translesion Synthesis Telomere Maintenance Via Semi-conservative Replication DNA Duplex Unwinding Nucleotide-excision Repair, DNA Incision Error-prone Translesion Synthesis DNA Damage Response, Detection Of DNA Damage Response To Organophosphorus Error-free Translesion Synthesis Positive Regulation Of DNA-directed DNA Polymerase Activity Regulation Of Signal Transduction By P53 Class Mediator	Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways		Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere Activation of ATR in response to replication stress PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Regulation of TP53 Activity through Phosphorylation Polymerase switching G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Alzheimer's disease ( 20061627) Colorectal cancer or advanced adenoma ( 30510241) Obesity-related traits ( 23251661)
Interacting Genes		8 interacting genes: ARFGAP1 BRD4 CHTF8 MESD PCNA RAD17 RFC1 RFC4	10 interacting genes: APP ATP6V1E1 BRD4 KPNB1 LRP5 MTNR1A PSMA5 RFC3 SNX5 SNX7
Entrez ID		5983	23184
HPRD ID		02676	12129
Ensembl ID		ENSG00000133119	ENSG00000117899
Uniprot IDs		A0A024RDQ8 P40938	Q14696
PDB IDs
Enriched GO Terms of Interacting Partners?
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