RCVRN and PQBP1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RCVRN	PQBP1
Description		recoverin	polyglutamine binding protein 1
Image
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Membrane Dendrite Perikaryon	Nucleus Nucleoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Neuronal Ribonucleoprotein Granule
	Molecular Function	Calcium Ion Binding Calcium Sensitive Guanylate Cyclase Activator Activity	DNA Binding Double-stranded DNA Binding Transcription Coactivator Activity Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Signal Transduction Visual Perception Phototransduction Positive Regulation Of Guanylate Cyclase Activity Regulation Of Calcium Ion Transport	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Regulation Of Transcription, DNA-templated Neuron Projection Development Positive Regulation Of Type I Interferon Production Regulation Of RNA Splicing Innate Immune Response Regulation Of Dendrite Morphogenesis Defense Response To Virus Cellular Response To Exogenous DsRNA Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade	mRNA Splicing - Major Pathway
Drugs		Myristic acid
Diseases			Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS) Non-syndromic X-linked mental retardation
GWAS
Interacting Genes		11 interacting genes: CAV1 GIT2 GRK1 GRK2 GRK5 GRK6 IL15RA PQBP1 SMAD3 TGFBR2 TOP1	24 interacting genes: APBB1 APP AQR ATXN1 CLTB EEF1A1 ERG28 ESR1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77
Entrez ID		5957	10084
HPRD ID		01558	02354
Ensembl ID		ENSG00000109047	ENSG00000102103
Uniprot IDs		P35243	A0A0S2Z4V5 O60828
PDB IDs		2D8N	4BWQ 4BWS 4CDO
Enriched GO Terms of Interacting Partners?
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