RBBP7 and MBD3L2

Number of citations of the paper that reports this interaction (PubMedID 15701600)
14

Data Source:
BioGRID (pull down)

		RBBP7	MBD3L2
Description		RB binding protein 7, chromatin remodeling factor	methyl-CpG binding domain protein 3 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol NuRD Complex ESC/E(Z) Complex	Nucleus
	Molecular Function	RNA Binding Protein Binding	Methyl-CpG Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Negative Regulation Of Cell Growth CENP-A Containing Nucleosome Assembly Post-translational Protein Modification Negative Regulation Of Gene Expression, Epigenetic Response To Steroid Hormone Negative Regulation Of G0 To G1 Transition Cellular Heat Acclimation Regulation Of Signal Transduction By P53 Class Mediator	Negative Regulation Of Transcription By RNA Polymerase II Methylation-dependent Chromatin Silencing
Pathways		PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines HATs acetylate histones RMTs methylate histone arginines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Neddylation Transcriptional Regulation by E2F6 HCMV Early Events
Drugs
Diseases
GWAS
Interacting Genes		33 interacting genes: APPL1 APPL2 BCL11A BCL11B BRCA1 BRMS1 BRMS1L CREBBP CYTOR DDB1 DHX30 ESR1 FOXK2 H3-4 H3C1 HDAC1 HDAC2 HUWE1 ING1 MBD3 MBD3L2 MTA2 NR2E3 PRKAA2 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUMO2 SUV39H1 TWIST1	10 interacting genes: CHD4 HDAC1 HDAC2 MBD2 MBD3 MTA1 MTA2 POLD3 RBBP4 RBBP7
Entrez ID		5931	125997
HPRD ID		04231	12139
Ensembl ID		ENSG00000102054	ENSG00000230522
Uniprot IDs		Q16576 Q6FHQ0	Q8NHZ7
PDB IDs		3CFS 3CFV
Enriched GO Terms of Interacting Partners?
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