ACTA2 and MINK1

Number of citations of the paper that reports this interaction (PubMedID 15032605)
1

Data Source:
HPRD (two hybrid)

		ACTA2	MINK1
Description		actin alpha 2, smooth muscle	misshapen like kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Filopodium Smooth Muscle Contractile Fiber Protein-containing Complex Cell Body Extracellular Exosome	Cytoplasm Golgi Apparatus Cytosol Postsynaptic Density Cell Junction Axon Dendrite Extracellular Exosome
	Molecular Function	ATP Binding Protein Kinase Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Muscle Contraction Regulation Of Blood Pressure Response To Virus Positive Regulation Of Gene Expression Vascular Smooth Muscle Contraction Positive Regulation Of Transcription, DNA-templated Glomerular Mesangial Cell Development Mesenchyme Migration	Regulation Of Cell-matrix Adhesion Protein Phosphorylation JNK Cascade Chemical Synaptic Transmission Multicellular Organism Development Regulation Of Mitotic Cell Cycle Regulation Of Cell-cell Adhesion Signal Transduction By Protein Phosphorylation Microvillus Assembly Regulation Of Cell Migration Stress-activated Protein Kinase Signaling Cascade Actin Cytoskeleton Reorganization Activation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis Dendrite Morphogenesis Positive Regulation Of P38MAPK Cascade Regulation Of AMPA Receptor Activity
Pathways		Smooth Muscle Contraction NOTCH4 Intracellular Domain Regulates Transcription	Oxidative Stress Induced Senescence
Drugs		Phenethyl Isothiocyanate
Diseases		Familial thoracic aortic aneurysm and dissection (TAAD); Aortic aneurysm familial thoracic type (AAT)
GWAS		Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic lymphocytic leukemia ( 26956414 23770605) Immunoglobulin A ( 20694011) Pulse pressure ( 30578418) Selective IgA deficiency ( 27723758)	Intracranial aneurysm ( 30823506) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Metabolite levels (lipid measures) ( 27005778) Multiple sclerosis ( 31604244)
Interacting Genes		18 interacting genes: CCT4 CCT5 CFL1 CREBBP DNASE1 EP300 GC MINK1 MYL1 MYOC PCYT1B PRKCD SELE SHBG SNTA1 TMSB4X UBE3A YBX1	14 interacting genes: ABI1 ACTA2 CALM3 CASKIN1 KIFAP3 MAP1B NCK1 NEDD4L NEFM PKP4 SPTBN2 TUBA1B YWHAB YWHAZ
Entrez ID		59	50488
HPRD ID		00031	11366
Ensembl ID		ENSG00000107796	ENSG00000141503
Uniprot IDs		D2JYH4 P62736	Q8N4C8
PDB IDs
Enriched GO Terms of Interacting Partners?
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